The Court of Arbitration for Sport has dismissed US cyclist Floyd Landis' appeal to overturn a positive doping test that resulted in the stripping of his 2006 Tour de France title.
The CAS upheld an earlier decision by the American Arbitration Association, saying that Landis would be banned for two years starting January 30, 2007.
It also ordered the disgraced cyclist to pay $US100,000 ($A104,500) to the US Anti-Doping Agency (USADA) as a contribution towards its costs in the CAS arbitration.
Landis was stripped of the 2006 Tour de France title after standing atop the podium following the final stage, when he tested positive for synthetic testosterone after the penultimate 17th stage of the race.
The American had fallen back in stage 16 but rallied in stage 17 to reclaim almost eight minutes on his way to a now-disgraced victory moment.
Landis denied any wrongdoing and appealed to the USADA in an open hearing last May. But the USADA panel ruled 2-1 against him, resulting in the two-year ban.
The International Cycling Union stripped Landis of his 2006 crown after that verdict, awarding the title to Spain's Oscar Pereiro.
Landis then brought the case to the global panel, attacking the credibility of the French laboratory which handled his doping samples.
In its ruling, the CAS said the laboratory "did not violate the International Standard for Laboratories".
It concluded that "the presence of exogenous testosterone or its precursors of metabolites in Floyd Landis' sample proves that he violated the anti-doping rules of the International Cycling Union".
